Secondary prophylaxis in rheumatic fever: is it time to change?
نویسندگان
چکیده
Background Carditis and rheumatic chronic heart disease are the most serious complications of Acute Rheumatic Fever. Nowadays prevention of recurrent episodes of group A b-hemolytic streptococcal pharyngitis is the most effective method to prevent the development of severe rheumatic heart disease. However the evidence of these guidelines are weak and result from studies conducted more than 50 years ago [1]. To detect rate of Carditis related to Acute Rheumatic Fever found at follow up and to find a relationship with clinical data at diagnosis and compliance to prophylaxis.
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RHEUMATIC FEVER IN lRANIAN CHILDREN: CLINICAL AND PREVENTIVE ASPECTS
A total of70 children aged 6 to 15 years with rheumatic fever and completed in-hospital data were reviewed from 19XX to 1993. In 5X.6% of patients this was the first attack of disease, while in 41.4'10 the episode represented a recurrence. Noncompliance of antimicrobial prophylaxis was noted in all of the subjects with recurrences. 61.4% of cases gave a previous history of sore throat, and ...
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